What did work was installing the x64 driver from Epson for their Epson Expression 1680 Professional scanner instead. I had to force the Device Manager driver install to use the .inf file for the 1680.
Here's how:
Download and run the Epson file.
It will extract to here: C:\EPSON\epson12203_twain_driver_and_epson_scan_utility_304a
cancel the install process.
Open Device Manager.
Right click the scanner (will have yellow "!")
click update driver
click "Browse my computer…."
click "let me pick from list..."
click have disk
browse to here: C:\EPSON\epson12203_twain_driver_and_epson_scan_utility_304a
pick any inf, and it should go from there.
Here's how:
Download and run the Epson file.
It will extract to here: C:\EPSON\epson12203_twain_driver_and_epson_scan_utility_304a
cancel the install process.
Open Device Manager.
Right click the scanner (will have yellow "!")
click update driver
click "Browse my computer…."
click "let me pick from list..."
click have disk
browse to here: C:\EPSON\epson12203_twain_driver_and_epson_scan_utility_304a
pick any inf, and it should go from there.