errors, warnings and reg. leaks!

Hey folks.
I suppose I should start by saying that I consider myself to have abouve averge computer skills in regards to OS, hardware and the. I also have below average typing skills.(superfast hunt and peck) I also know enough to know when to stop chasing files and ask someone else!
So heres the deal.I noticed a few days ago my system was acting quirky. "window exploer stopped working;Outlook has encountered anerrer..." things like that. Iknow my system fairly well(not great). I just started using x64 Home Premium like 6 mos ago. (Former XP Pro lover) Yeah I know, late bloomer. I use Malwarebytes, Defender, as well as Superantispy (on bootable CD with PE). Nice. Most of which I use every few days,if not more. None of which found any issues. My antivirus on the other hand seems to have detected, but says was unable to repair/quarrantine.
From Trend Micro internet security:



Possible_Hifrm-5C:\Users\JaderCo\AppData\Local\Microsoft\Windows\Temporary Internet Files\Low\Content.IE5\4M11433N\505529[1].htm


The log files it had are no longer present.(No worries,I made a manual log before it dissappeared
There are a few other log files I saved as well, along with event viewer logs.
Sorry, but I didnt want to take liberties and post a loig without being asked for one. Seemed rude. But here are a fre of the errors I found, as well as some processes that I feel certain are NOT OS files or exe.
Warning: Event ID 1530 detected reg file in use bu another process...file will be unloaded.
Details:28 reg handles leaked byuser\registry**** Trend Micro***
Error event ID 10description here)...because of error 0x80041003
Security auditing numerous...
system error event ID 10016 DistributedCOM
as well as 349 code intergrity errors....sheesh
I could go on, but I suppose logs would be easier. Being gunshy as I am about this sorta thing, I made manual log files for Trend, Resourse manager, as well as snippets showing my cpu's maxed out, and HDD's working to the limit.(Caviar Black 750Gb X2 ) Non-Raid
I have to leave you with this though. Amusing. (NOT)
I tried opening task manager, I geta msh "disk not found.Please insert disk into drive D:\ and try again" Hows that for special?
I hope this is enough info for now. ( I had a lengthy description in detail all typed out after 30 min or coping file names and such, only to have this connection time out) Lost it all and here I am again.
Thanks Again!

OK, so looking back at my post it does seem a little lacking in info. At least theres no typos...
I have been trying to narrow down what is writing to my disks, and robbing my memory.
This is what I've done so far, and what I found:
Disabled Machine Script Debugger.
Disabled indexing.
Remot access conn manager was using TONS of resources. I couldnt disable it in services(options were shaded out) But I managed to taskkill it.Not sure if the Perfmon events are relevant, seeing how resources are being vamped,but just to give a few:
Event 302
Event 351
Mostly stating usb drivers causing issues...?Oh, and I was able to open task manager. In the resource monitor, the image name is Taskmgr...the description is Acronis disk director. No clue there.
Localsystemnetworkrestricted (SVCHOST.exe is doing the majority of the read/write Its eve trying to write files to 2nd drive. Seems to be backup files, but I have auto backup off.
I just checked perfmon, and now LOTS of files being written to I:\ drive.
I'm leaning toward Trend being corrupt, and allowing an event to occur that triggered this mess. It says summary report for past 2 days 0 incidents. I just copied its log stating an infection this morning,so...yeah.
One process SFCTLCOM.exe description was to control all Trend functions. It now says TMPWF.exe controls all Trend functions.
Could Acronis be running somewhere doing this? An NTFS volume log is being written there. And the process snapman.exe is popping up a lot. Part of Acronis. I just found it a SnapMan.sys file in my I: drive driver files...partmgr.sys and snapman.sys along with disk.sys.
OK,well thats about all the info I can manage for now. Hope this extra info is somewhat useful.
Thanks