Toshiba Satellite A 300 with Vista x64 will no longer boot up

After a power outage Vista will no longer boot. I am unable to get a successful boot into Windows Vista operating system. It seems the boot file or the registry have misplaced pointers or corruption.

Powering on I was only able to reach the Bios settings. The initial error message was Status: 0xc00000e9 an unexpected I/O error.

More recently it is : 0xc000000f windows failed to load because the system registry file is missing or corrupt

This Toshiba laptop did not come with a Vista OS CD so I have purchased the Vista x64 Easy BCD Recovery CD from Neosmart. None of the tools have been able to fix the problem /s

The Automated Repair function log states : No O/S found
Repair required is the partition table
Failed Error Code : 0x 490

I have been reading threads here and running a variety of diagnostics to try and determine what the problem is without any success so far.

Bootrec.exe / rebuildBCD produces the error " the request could not be performed because of an I/O device error "

BCDedit.exe /enum " boot configuration data store could not be opened. Cannot find the specified file. "

SFC / Scannow produces the error " windows resource protection could not start the repair service "

Chkdsk fails to complete successfully indicated an unexpected error was experienced.

Would very much appreciate the exceptional expertise of the wizards here.

Hello.. see if you can use Ubuntu Live CD to boot up : Use Ubuntu Live CD to Backup Files from Your Dead Windows Computer - How-To Geek
You may need to perform a hard drive diagnostic : HD Diagnostic You would want to use short and the long test.
Please post back results .